Single-nucleus RNA sequencing reveals the shared mechanisms inducing cognitive impairment between COVID-19 and Alzheimer’s disease
Published in Front Immunol., 2022
I finished this article in Beihang University with Dr. Zhirong GUO and under the supervision from Dr. Shaocong MO and Prof. Wenchao GU in 2022.
In this work, we pioneer the identification of shared genetic pathways between Alzheimer’s disease (AD) and COVID-19-induced cognitive impairments, utilizing integrated single-nucleus RNA-sequencing data to uncover novel targets for therapeutic intervention. Our findings illuminate potential avenues for preventing and treating cognitive dysfunction in COVID-19 patients, marking a significant step forward in neurodegenerative disease research.
This article receives attention from 10X Genomics:
Recommended citation: Yifan Fu, Zhirong Guo, et al. (2022). Front Immunol. 13:967356. https://doi.org/10.3389/fimmu.2022.967356